Immuno-modulatory effects of vitamin D3 in human monocyte and macrophages
M Di Rosa, G Malaguarnera, C De Gregorio… - Cellular …, 2012 - Elsevier
Vitamin D3 [1α, 25-(OH) 2D3], involved in the regulation of body calcium homeostasis,
promotes immature myeloid precursor cells differentiation into monocytes/macrophages. In
this study we compared the regulatory interaction between 1α, 25-(OH) 2D3 and tumor
necrosis factor (TNF)-α or lipopolysaccharide (LPS) in the mRNA expression of interleukin
(IL)-1β,(IL)-6, TNF-α, toll like receptors (TLR)-2 and (TLR)-4 in freshly isolated human
monocyte (MonoT0) and in macrophages cultured for seven days (MØT7). Additionally, we …
promotes immature myeloid precursor cells differentiation into monocytes/macrophages. In
this study we compared the regulatory interaction between 1α, 25-(OH) 2D3 and tumor
necrosis factor (TNF)-α or lipopolysaccharide (LPS) in the mRNA expression of interleukin
(IL)-1β,(IL)-6, TNF-α, toll like receptors (TLR)-2 and (TLR)-4 in freshly isolated human
monocyte (MonoT0) and in macrophages cultured for seven days (MØT7). Additionally, we …
